AHK-Cu

Copper Tripeptide • Hair Follicle & Dermal Biology Research

For Research Use Only

Overview

AHK-Cu (Alanyl-Histidyl-Lysine Copper) is a copper-binding tripeptide consisting of the amino acids alanine, histidine, and lysine complexed with Cu²⁺.

AHK-Cu is structurally related to GHK-Cu but differs at its first amino acid. Researchers have investigated AHK-Cu primarily for its interactions with human hair follicles, dermal papilla cells, cellular proliferation, and copper-peptide signaling.

Research Areas

AHK-Cu has been investigated in research involving:

• Hair-follicle biology
• Dermal papilla cells
• Follicular growth signaling
• Cellular proliferation
• Cellular survival pathways
• Copper-peptide biology
• Dermal physiology
• Fibroblast research
• Tissue and cellular signaling
• Cosmetic-science research

The evidence base remains preclinical. The key published study used isolated human hair follicles and cultured human dermal papilla cells rather than treating human participants.

Mechanism Being Studied

Researchers have investigated AHK-Cu for potential effects involving:

• Dermal papilla-cell proliferation
• Hair-follicle elongation
• Cellular survival signaling
• Bcl-2/Bax-associated pathways
• Caspase-related apoptotic signaling
• Copper-dependent cellular processes

In a 2007 laboratory study, specific low concentrations of AHK-Cu increased the elongation of isolated human hair follicles and proliferation of cultured dermal papilla cells. Researchers also observed changes in molecular markers associated with apoptosis.

Why Researchers Study AHK-Cu

The dermal papilla plays an important role in regulating the development and growth cycle of hair follicles.

Because AHK-Cu demonstrated activity in dermal papilla cells and isolated human follicles under experimental conditions, researchers have investigated it as a tool for studying:

• Hair-follicle physiology
• Follicular growth signaling
• Dermal papilla-cell behavior
• Copper-peptide interactions
• Cellular proliferation
• Cell-survival pathways

However, laboratory findings should not be interpreted as proof that AHK-Cu treats hair loss or produces hair growth in people. Controlled human clinical evidence specific to AHK-Cu remains lacking.

AHK-Cu vs. GHK-Cu

Although closely related, these are different research compounds:

AHK-Cu: Ala-His-Lys + Copper
GHK-Cu: Gly-His-Lys + Copper

GHK-Cu has a substantially larger research literature involving skin and extracellular-matrix biology. AHK-Cu’s direct published evidence is much narrower and focuses primarily on hair-follicle and dermal-papilla models. Evidence for one compound should therefore not automatically be attributed to the other.

Product Features

✔ Premium Research Grade
✔ High-Purity AHK-Cu
✔ Copper-Binding Tripeptide
✔ Third-Party Tested (COA Available)
✔ Identity & Purity Verification
✔ Secure Professional Packaging
✔ Laboratory Research Only

Common Research Applications

Researchers have explored AHK-Cu in studies involving:

• Hair-follicle biology
• Dermal papilla-cell physiology
• Copper-peptide signaling
• Cellular proliferation
• Cellular survival
• Dermal research
• Follicular signaling
• Cosmetic-science research

Storage

Store according to the product’s batch-specific stability documentation. Protect research material from excessive heat, moisture, and direct sunlight.

Following preparation for laboratory experiments, use validated laboratory storage and handling procedures and minimize unnecessary temperature cycling.

Disclaimer

For Research Use Only.

AHK-Cu is an experimental research compound. There is currently no established human dosing regimen or FDA-approved therapeutic indication for AHK-Cu.

This product is intended exclusively for laboratory research and analytical purposes.

Not intended for human or veterinary use.

Why Choose Voltis Research Co.

At Voltis Research Co., quality begins with verification. Researchers deserve confidence that the compound identified on every vial accurately represents the material being investigated.

Qualifying batches undergo independent third-party analytical testing, with batch-specific Certificates of Analysis available to document identity and purity.

The Voltis Commitment

⚡ Research-Grade Quality
⚡ Independent Third-Party Testing
⚡ Batch-Specific Certificate of Analysis (COA)
⚡ High-Purity Research Peptides
⚡ Rigorous Quality Control
⚡ Secure Professional Packaging
⚡ Transparency, Consistency & Reliability

Powering Discovery Through Quality Research.