5-AMINO-1MQ
NNMT Inhibitor • Metabolic & Cellular Energy Research Compound
For Research Use Only
Overview
5-Amino-1MQ (5-amino-1-methylquinolinium) is an experimental small-molecule compound studied primarily as an inhibitor of nicotinamide N-methyltransferase (NNMT).
NNMT is an enzyme involved in nicotinamide metabolism and cellular methylation pathways. Because these pathways intersect with NAD⁺ metabolism, energy regulation, adipose-tissue biology, and skeletal-muscle physiology, NNMT has become an important target in metabolic research.
Research Areas
5-Amino-1MQ has been investigated in preclinical research involving:
- NNMT inhibition
- Cellular energy metabolism
- NAD⁺-related metabolic pathways
- Adipose-tissue biology
- Lipid metabolism
- Glucose metabolism
- Insulin-sensitivity models
- Skeletal-muscle physiology
- Metabolic dysfunction
- Cellular methylation pathways
Studies have included cultured cells, mice, and rat pharmacokinetic models. Human therapeutic effects have not been established.
Mechanism Being Studied
Researchers primarily investigate 5-Amino-1MQ for its ability to inhibit NNMT.
NNMT normally transfers a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA).
Researchers are therefore studying how NNMT inhibition may influence:
- Nicotinamide metabolism
- NAD⁺ salvage-pathway biology
- SAM-dependent methylation
- Cellular energy regulation
- Adipocyte metabolism
- Glucose homeostasis
- Metabolic flexibility
Laboratory research has demonstrated that 5-Amino-1MQ can reduce intracellular 1-MNA concentrations through NNMT inhibition.
Why Researchers Study 5-Amino-1MQ
NNMT has emerged as an interesting metabolic research target because its activity connects several important cellular systems involving nicotinamide, NAD⁺ biology, methyl-group metabolism, and energy regulation.
Researchers have used 5-Amino-1MQ to investigate relationships between:
- NNMT activity
- Energy metabolism
- Adipose-tissue function
- Body-composition changes in animal models
- Glucose regulation
- Skeletal-muscle metabolism
- Cellular NAD⁺ pathways
In diet-induced-obesity mouse models, researchers reported changes in fat mass, glucose tolerance, insulin sensitivity, and liver metabolic markers following NNMT inhibition. These are animal findings and should not be presented as established weight-loss or metabolic effects in humans.
Product Features
✔ Premium Research Grade
✔ High-Purity 5-Amino-1MQ
✔ NNMT Research Compound
✔ Third-Party Tested (COA Available)
✔ Identity & Purity Verification
✔ Secure Professional Packaging
✔ Laboratory Research Only
Common Research Applications
Researchers have explored 5-Amino-1MQ in studies involving:
- NNMT enzyme biology
- NAD⁺-associated metabolism
- Cellular bioenergetics
- Adipocyte physiology
- Lipid metabolism
- Glucose metabolism
- Skeletal-muscle research
- Metabolic signaling
- Pharmacokinetic research
Storage
Store according to the product’s batch-specific stability documentation. Protect research material from excessive heat, moisture, and direct sunlight.
Use validated laboratory storage and handling procedures appropriate to the specific chemical form supplied by Voltis.
Disclaimer
For Research Use Only.
5-Amino-1MQ is an experimental small-molecule research compound, not a peptide. Published evidence supporting its metabolic effects remains primarily preclinical, and the available literature does not establish a therapeutic human dosing regimen, safety profile, or clinical weight-loss effect.
This product is intended exclusively for laboratory research and analytical purposes.
Not intended for human or veterinary use.
Why Choose Voltis Research Co.
At Voltis Research Co., quality begins with verification. Researchers deserve confidence that the compound identified on every product accurately represents the material being investigated.
Qualifying batches undergo independent third-party analytical testing, with batch-specific Certificates of Analysis available to document identity and purity.
The Voltis Commitment
⚡ Research-Grade Quality
⚡ Independent Third-Party Testing
⚡ Batch-Specific Certificate of Analysis (COA)
⚡ High-Purity Research Compounds
⚡ Rigorous Quality Control
⚡ Secure Professional Packaging
⚡ Transparency, Consistency & Reliability
Powering Discovery Through Quality Research.
5-Amino-1MQ (50 mg Vial) Dosage Protocol
