IGF-1 LR3

Long-Acting IGF-1 Analog Research Peptide

For Research Use Only

Overview

IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1) is a modified analog of naturally occurring IGF-1, an important signaling molecule involved in cellular growth, differentiation, metabolism, and tissue development.

IGF-1 LR3 contains an altered amino-acid sequence and an extended N-terminal region. These modifications were designed to reduce its interaction with certain IGF-binding proteins (IGFBPs) and provide prolonged biological activity compared with native IGF-1 in experimental systems.

Because of these properties, IGF-1 LR3 is widely used as a laboratory tool for investigating the IGF-1 receptor pathway, cellular proliferation, skeletal-muscle biology, glucose metabolism, and anabolic signaling.

Research Areas

IGF-1 LR3 has been investigated in laboratory and preclinical research involving:

• IGF-1 receptor signaling
• Cellular growth and proliferation
• Protein-synthesis pathways
• Skeletal-muscle physiology
• Muscle-cell differentiation
• Satellite-cell biology
• Glucose and nutrient metabolism
• Tissue growth and remodeling
• PI3K/AKT signaling
• Cellular survival pathways

IGF-1 LR3 is an experimental research compound and does not have an established FDA-approved therapeutic use.

Mechanism Being Studied

Researchers primarily study IGF-1 LR3 for its interaction with the IGF-1 receptor (IGF-1R).

Activation of IGF-1R can influence several downstream signaling pathways, including:

PI3K → AKT → mTOR

These pathways participate in processes involving:

• Protein synthesis
• Cellular proliferation
• Cell survival
• Glucose uptake
• Cellular differentiation
• Tissue growth and remodeling

The structural modifications of LR3 also give researchers a way to investigate IGF signaling with less influence from some IGF-binding proteins than occurs with native IGF-1.

Why Researchers Study IGF-1 LR3

The GH/IGF-1 axis is one of the major signaling systems involved in mammalian growth and tissue development.

Researchers use IGF-1 LR3 to better understand how IGF signaling influences:

• Muscle-cell development
• Cellular hypertrophy pathways
• Protein metabolism
• Nutrient utilization
• Tissue remodeling
• Cellular regeneration
• Growth-factor signaling

Its modified structure and extended activity make IGF-1 LR3 particularly useful in controlled experimental models where sustained IGF-1 receptor stimulation is being investigated.

Product Features

✔ Premium Research Grade
✔ High-Purity IGF-1 LR3
✔ Third-Party Tested (COA Available)
✔ Identity & Purity Verification
✔ Secure Professional Packaging
✔ Laboratory Research Only

Common Research Applications

Researchers have explored IGF-1 LR3 in studies involving:

• Growth-factor biology
• IGF-1 receptor signaling
• Skeletal-muscle research
• Cellular proliferation
• Protein-synthesis pathways
• Metabolic signaling
• Satellite-cell physiology
• Tissue-remodeling models
• PI3K/AKT/mTOR signaling

Storage

• Store according to the product’s batch-specific stability documentation.
• Protect lyophilized material from excessive heat, moisture, and direct sunlight.
• Following preparation for laboratory experiments, use validated laboratory storage procedures.
• Minimize unnecessary temperature cycling and repeated freeze-thaw exposure.

Disclaimer

For Research Use Only.

This product is intended exclusively for laboratory research and analytical purposes.

IGF-1 LR3 is not approved by the U.S. Food and Drug Administration (FDA) for the diagnosis, treatment, cure, or prevention of disease and is not intended for human or veterinary use.

Why Choose Voltis Research Co.

At Voltis Research Co., quality and transparency aren’t extras—they’re fundamental to reliable research.

Our qualifying batches undergo independent third-party analytical testing, with batch-specific Certificates of Analysis available to document identity and purity. From sourcing through final packaging, Voltis emphasizes consistency, traceability, and rigorous quality control.

The Voltis Commitment

⚡ Research-Grade Quality
⚡ Independent Third-Party Testing
⚡ Batch-Specific Certificate of Analysis (COA)
⚡ High-Purity Research Peptides
⚡ Rigorous Quality Control
⚡ Secure Professional Packaging
⚡ Transparency, Consistency & Reliability

Powering Discovery Through Quality Research.

IGF-1 LR3 (1 mg Vial) Dosage Protocol